Question

Dados sobre células HEK293?

Answer 1

Eis artigo fundamental sobre células HEK293:

• Stepanenko AA, Dmitrenko VV. HEK293 in cell biology and cancer research: phenotype, karyotype, tumorigenicity, and stress-induced genome-phenotype evolution. Gene. 2015 Sep 15;569(2):182-90. [PMID: 26026906]

Answer 2

Dados sobre o genoma da HEK293:

• Lin, Y.-C., Boone, M.,Meuris, L., Lemmens, I., Van Roy, N., Soete, A., Reumers, J., Moisse,M., Plaisance, S., Drmanac, R., Chen, J., Speleman, F., Lambrechts, D., Van de Peer, Y., Tavernier, J., Callewaert, N., 2014. Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations. Nat. Commun. 5, 4767. [PMID: 25182477]
• Base para comparação dos genomas de 6 variantes de HEK293: http://hek293genome.org/v2/